Some people still dont use enough tools to keep theyr system virus,spyware,adware free.
I think this is VERY important to know.
Checklist 101

My recommendations:
-Norton virus scan 2004
-Adaware SE
-Spy bot search and destroy
-No Adaware
( consider bying this if your a p2p user )
-Popupcop
( blocks scripts better then any other popupblocker ive tried so far)
-Get any BHO remover, if your browser is acting odd or changing your homepage by itself or getting popups out of nowhere then this will give you a better chance of removing them.

Ive been asked this and there is no need to worry,
Wincustomize does not have viruses in theyr popups.

If you have any suggestions for any other good anti spyware etc program post it

I hope I helped a few out there